amitotically::This and other homologydependent maternal effects have suggested that rearrangement patterns are epigenetically determined by an rnamediated, trans nuclear comparison, involving the rna interference pathway, of germline and somatic genomes amitotically

amitotically::This and other homologydependent maternal effects have suggested that rearrangement patterns are epigenetically determined by an rnamediated, trans nuclear comparison, involving the rna interference pathway, of germline and somatic genomes.
Results: we report the identification of novel developmentally regulated rna binding proteins, nowa1p and nowa2p, which are required for the survival of sexual progeny.
Conclusions: the results indicate that nowa proteins are essential components of the trans nuclearcrosstalk mechanism that is responsible for epigenetic programming of genome rearrangements.
We discuss implications for the current models of genome scanning in ciliates, a process related to the formation of heterochromatin by rna interference in other eukaryotes.